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This application note demonstrates the comprehensive sequence analysis and localization of modifications in three synthetic GLP-1 analogs.
In this study we demonstrate in-depth LC-MS/MS sequence and modification characterization of multiple GLP-1 receptor agonists by implementing electron capture dissociation and ExDViewer for fragment analysis.
In-source chemical charge reduction allows precise control over protein charge distributions. This work explores the influence of charge reduction on protein structure and top-down fragmentation.
ExDViewer is a flexible fragment analysis software that enables streamlined characterization of synthetic peptide sequences. Here, we highlight key features such as customizable fragmentation rules that were key for analyzing biomimetic peptoid ECD...