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This application note presents a streamlined LC/MS workflow for ASO purity assessment using the Agilent InfinityLab Pro iQ Plus LC/MS system and Oligo Analysis Accelerator (OAA) software for Agilent OpenLab CDS.
In this application note, HILIC is introduced as an orthogonal methodology and applied to the analysis of Exenatide, Semaglutide, and Tirzepatide.
This guide is valid for LC/SQ Mass Detector systems running OpenLab CDS 2.7 or 2.8 with LC/MS Driver 3.2
Release notes for the LC/SQ driver
LC/MS-based method for assessing the purity of an antisense oligonucleotide
Site preparation checklist for the InfinityLab Pro iQ Series LC/SQ mass detectors
This guide provides an overview of the daily workflow using OpenLab CDS software
The novel approach presented in this method utilizes standard chromatographic methods and simple cost-effective single quadrupole mass spectrometer without sacrificing accuracy for the screening and quantitation of histamines in Gentamicin matrices.
Accurate Mass Full Spectral Monitoring and Analysis of Both the Analyte and Reference Standard with Ion Chromatography – Mass Spectrometry.
A robust microflow method for oligonucleotide analysis which dramatically reduces the consumption of HFIP and TEA. Carried out using the Axcend Focus LC ? coupled with the Agilent LC/MSD Pro iQ Plus.
A robust and cost-effective single quadrupole mass spectrometer reports on glycosylation relative abundances for monoclonal antibodies.
This study evaluates the stability of tirzepatide and semaglutide under various pH and storage conditions using the Agilent InfinityLab Pro iQ Plus LC/MS system.
This poster is a demonstration of Pro iQ Plus robustness & ruggedness against these factors over a series of 800 consecutive injections of analytes spiked in crashed plasma matrix.
Establish correlations between abundance settling time and changes in multiple acquisition parameters from empirical data. Apply the correlations to ensure instrument performance at a high sampling rate with minimal inter-measurement delays.
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| Chinese (Simplified) (China) | Complete (PDF) |
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本應(yīng)用說(shuō)明介紹了一種分析 26 種全氟和多氟烷基化合物 (PFAS) 標(biāo)準(zhǔn)品的方法。
本研究采用高效液相色譜 (HPLC) 系統(tǒng)結(jié)合 Agilent InfinityLab Pro iQ Plus 質(zhì)譜檢測(cè)器，監(jiān)測(cè)不同 pH 值和儲(chǔ)存條件下替爾泊肽的雜質(zhì)情況。
使用 Agilent InfinityLab Pro iQ Plus 單四極桿 LC/MS 系統(tǒng)在完整蛋白質(zhì)和亞基水平監(jiān)測(cè)抗體的糖基化。
本應(yīng)用簡(jiǎn)報(bào)介紹了使用 Agilent InfinityLab Pro iQ Plus LC/MS 系統(tǒng)對(duì)合成寡核苷酸進(jìn)行中高通量分子確認(rèn)的實(shí)用方法。