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This application note presents a streamlined LC/MS workflow for ASO purity assessment using the Agilent InfinityLab Pro iQ Plus LC/MS system and Oligo Analysis Accelerator (OAA) software for Agilent OpenLab CDS.
In this application note, HILIC is introduced as an orthogonal methodology and applied to the analysis of Exenatide, Semaglutide, and Tirzepatide.
This guide is valid for LC/SQ Mass Detector systems running OpenLab CDS 2.7 or 2.8 with LC/MS Driver 3.2
Release notes for the LC/SQ driver
LC/MS-based method for assessing the purity of an antisense oligonucleotide
Site preparation checklist for the InfinityLab Pro iQ Series LC/SQ mass detectors
To get you started and to assure a successful and timely installation, please refer to this specification or set of requirements.
This application note confirms the aggregates of liraglutide and semaglutide through size exclusion chromatography using an Agilent 1290 Infinity II Bio LC system and InfinityLab LC/MSD XT.
This application note presents the analysis of peptide-related impurities for semaglutide with the Agilent 1290 Infinity II bio 2D-LC and InfinityLab LC/MSD XT.
This application note highlights the analysis and identification of impurities arising from stability assays with GLP-1 agonist peptides.
This application note utilizes the 1260 Infinity II Bio Prime LC and InfinityLab LC/MSD iQ for the confirmation of GLP-1 (Liraglutide) sample.
Molecular weight confirmation and simple characterization workflows for synthetic oligos with Agilent LC/MSD XT and MS Spectral Deconvolution feature in OpenLab CDS 2.8.
In this application note, a method was presented to quantify major components as well as degradation products of lithium-ion battery electrolytes, with particular attention to achieving separation of all analytes within 14 minutes.
The advantage of using the Agilent 1290 Infinity II Bio LC System with the Agilent InfinityLab LC/MSD iQ for these challenging analytes is demonstrated.
This guide contains safety and regulatory information for your Agilent 6000 Series LC/MS system.
Interactive Site Prep Guide for all LC/MS instruments. Download, unzip, and run index.htm.
This Technical Note describes the installation/replacement of injection loops, tubing kits, and capillaries on the G7158B Open-Bed Sampler/Collector.
Agilent InfinityLab LC Purification Solutions offer high-performance instrumentation, columns, software, and services for analytical- to preparative-scale workflows.
Agilent Load & Lock Columns are ideal for routine purification of large quantities of material. Download brochure to learn more.
This Application Note describes a routine analysis workflow for pharmaceutical QA/QC labs.
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