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Agilent PLRP-S column demonstrates superior separation performance for the analysis of mAbs and ADC at both intact and fragment levels
AdvanceBio Desalting - RP cartridges used for effective desalting of LC-separated monoclonal antibodies (mAbs) before characterization by mass spectrometry
In this paper, we are investigating an antibody drug conjugate (ADC) with a cysteine linker.
Resolve mAbs faster and better with Agilent AdvanceBio RP-mAb columns.
An Agilent Bio-Monolith Protein A column determined recombinant mAb titer and was used to enrich μg amounts of antibody for further structural characterization by MS.
The charge heterogeneity provides a great challenge for the complete characterization of the monoclonal antibody (mAb).
This work describes a high flow LCMS method to demonstrate the high resolution mass analysis of mAbs with good chromatography and its utility in analysis of Biosimilar mAbs.
| Publication Part Number | 5991-4266EN | ||
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A comparison of the separation and sequence coverage of glycoproteins by reversed-phase and HILIC demonstrates the utility of HILIC.
| Publication Part Number | 5991-2085EN | ||||
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Fast and efficient LC TOF/MS characterizes intact and digested IgG to identify glycoform masses and profiles. mAb-glyco chip analysis built a glycan accurate mass database.
| Publication Part Number | 5990-2323EN | ||||
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Accurate mass intact protein analysis using 6550 iFunnel Q-TOF
| Publication Part Number | 5991-2116EN | |||
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