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In this application note, we profiled the N-glycans of several monoclonal antibodies with the new Agilent AdvanceBio Amide HILIC column.
A method for analyzing primary amino acids in cell culture media using AdvanceBio Amino Acid Analysis (AAA) solution with absorbance detection
Agilent Bio-Monolith Protein G quantitates supernatant mAbs across a wide loading range at many flow rates, complementing Protein A for fast titer analysis.
Application note for the rapid analysis of adenoviruse type 5 particles with bio-monolith anion-exchange HPLC Columns
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This application note describes use of the Agilent AdvanceBio sialic acid profiling and quantitation kit (p/n GS24-SAP) to profile sialic acid species present and perform absolute sialic acid quantitation.
Method ransfer from a 1260 Infinity Bio-inert LC to a 1260 Infinity II Bio-inert LC showing proof of equivalency for charge variant analysis of rituximab
"This Application Note describes the quantification of aggregates in biotherapeutic
Agilent PLRP-S column demonstrates superior separation performance for the analysis of mAbs and ADC at both intact and fragment levels
AdvanceBio Desalting - RP cartridges used for effective desalting of LC-separated monoclonal antibodies (mAbs) before characterization by mass spectrometry
Small –scale purification of a monoclonal antibody from a cell lysate and the subsequent analysis on a single instrument, the Agilent 1260 Infinity Bio-inert Quaternary LC.
| Publication Part Number | 5991-1195EN | ||||
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In this paper, we are investigating an antibody drug conjugate (ADC) with a cysteine linker.
Anion Exchange Chromatography with Agilent Bio HPLC columns and 1260 Infinity Bio-Inert LC System
Resolve mAbs faster and better with Agilent AdvanceBio RP-mAb columns.
Agilent Bio-Monolith Protein A delivers high-throughput, precise, accurate, linear, and robust separation of mAbs to optimize clone selection and cell cultures.
A versatile Agilent Bio-Monolith Protein A column analyzed an optimized recombinant mAb manufactured with desired structural characteristics.
An Agilent Bio-Monolith Protein A column determined recombinant mAb titer and was used to enrich μg amounts of antibody for further structural characterization by MS.
An Agilent 2.7 μm HILIC column revealed a glycopeptide not seen by RP. HILIC can be orthogonal and complementary to RP for better retention of hydrophilic peptides.
This Application Note shows the workflow solution for the physicochemical and biological characterization of a biosimilar and innovator rituximab.
The charge heterogeneity provides a great challenge for the complete characterization of the monoclonal antibody (mAb).
This work describes a high flow LCMS method to demonstrate the high resolution mass analysis of mAbs with good chromatography and its utility in analysis of Biosimilar mAbs.
| Publication Part Number | 5991-4266EN | ||
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