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In this work we investigate ways to tune the CIU-IM-ECD-MS to yield practical ECD efficiency and IM resolution leveraging the prototype ExD cell to study the relationship between protein collision cross section (CCS) and sequence coverage by ECD.
This poster introduces a chemical charge stripping method to lower the number of charge states with a hope to maintain the unfolded protein structure.
In this study, we performed a proof-of-concept study in human plasma samples using Uniprot human reference proteome, PeptideAtlas plasma spectral libraries, Skyline software and 6495D LC/TQ system.
Discover Impactful Pathway Information with Multi-Omic Studies Using easily Transferable Methods.
In this study, we demonstrate use of an RT simulation curve for predicting retention times of oxylipins lacking standards using a previously published article. The method offered highly selective separation and sensitive detection in qualitative and...
In this poster we highlight a highly specific, sensitive, and reproducible method that was developed for the quantitation of N-nitroso dabigatran etexilate impurity in dabigatran etexilate mesylate drug substance using the 6495C triple quadrupole...