??? ?? ??? ??? ?? ?? ??? PL-SAX ??? ?? ??
????? PL-SAX ??? ?? HPLC ??
PL-SAX ? ??? ?? ??? ???? ?? ??? ????? ??? ?? ???????. PL-SAX ??? ??? ??? ?? ?? ???? ???? ?? ??????????? ??? ?? ??? ??????.
PL-SAX ??? ??? ?? ??? ??? ???, ?? HPLC ???? ??? ? ???? ?????. ????? ??? ???? ?? ??? ? ??? ?? ???? ?? ?? pH ????? ??? ?? ??? ???? ??? ?? ??? pH? ?????. ??? ???? ?? ?? ?? ? ???? ??? ? ???, ?? ?? ???(self-complementary) ???? ?? ?? ?????????? ?? ? ??? ?? ?? ? ???/?? ??? ??? ???? ???.
PL-SAX ??? ??? ?? ??? ??? ???, ?? HPLC ???? ??? ? ???? ?????. ????? ??? ???? ?? ??? ? ??? ?? ???? ?? ?? pH ????? ??? ?? ??? ???? ??? ?? ??? pH? ?????. ??? ???? ?? ?? ?? ? ???? ??? ? ???, ?? ?? ???(self-complementary) ???? ?? ?? ?????????? ?? ? ??? ?? ?? ? ???/?? ??? ??? ???? ???.
- Charge Variant Analysis
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- pH ?? 1-14; ??? ?? ??? ??
- ?? ??: 80°C
- ? ?? ??? ?? ??? ???
- ??? ??? ??? ? ??? ?? ??? ?? ??
- ?? ?? ??? ?? ? ?? ??? ??, ???? ?? ??
- ??? ?? ? ??? ??? ?? ???? ?? ??
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Optimizing Separation of Oligonucleotides with Anion-Exchange Chromatography
This application note describes common method parameters that can be optimized when purifying oligonucleotides ranging from 25 to 100 bases in length.
- Application Notes
- English
- 11 Apr 2022
- 416.32 KB
Ion Exchange Chromatography for Biomolecules: Method Development and Troubleshooting Tips
Technical overview describing ion exchange method development and troubleshooting
- Technical Overviews
- English
- 12 Nov 2025
- 465.86 KB
Scalable Purification of a Synthetic Oligonucleotide Using Agilent PL-SAX Columns
This application note highlights excellent performance of Agilent PL-SAX columns for synthetic oligonucleotide analysis and suggests an optimal kickoff for exploring alternative method conditions.
- Application Notes
- English
- 02 Jun 2025
- 569.53 KB
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Bio LC ?? ??? ???
??? ????? ?? ????, ?? ? ?? ??, ?? ??, ??? ?? ?? ? ???? ??? ??? ???? ? ??? ?? ??? ???? ????.
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