AdvanceBio Surfactant Profiling HPLC columns are designed to quickly and reproducibly characterize non-ionic surfactants and their degradation products, particularly in biologic formulation buffer. The unique selectivity of this reversed-phase column allows for excellent separation and high resolution of the various components of the surfactants. The 3.5 μm particle size allows for robustness with samples in heavy matrix such as formulation buffer, while maintaining excellent separations.

Every batch of the AdvanceBio Surfactant Profiling media is tested with a mix of a polysorbate and its major fatty acid to ensure resolution and reproducibility. With regulatory bodies increasing scrutiny on polysorbate degradation and its adverse effects, it’s prudent to proactively incorporate this analysis in development labs now. The AdvanceBio Surfactant Profiling HPLC column is the best-in-class column to characterize degradation in polysorbates and other surfactants.