ZORBAX 300 ? HPLC columns are designed for efficient and reproducible separations of high-molecular-weight analytes. Featuring a wide-pore (300 ?) structure, these columns ensure complete access to the bonded phase, enabling optimal interaction and resolution for peptides, proteins, and other large biomolecules.

300StableBond (300SB) columns offer exceptional stability under low pH conditions, making them ideal for use with mobile phases containing trifluoroacetic acid (TFA), formic acid, or acetic acid, perfect for robust LC/MS workflows. For applications requiring high pH stability, Extend-C18 columns offer enhanced stability and alternative selectivity under high pH conditions.

Available in seven bonded phases (Diphenyl, SB-C3, SB-C8, SB-C18, SB-CN, Extend-C18, and HILIC), ZORBAX 300 ? columns provide versatile selectivity across a broad range of applications. For challenging protein separations, these columns can be operated at temperatures up to 80?°C. Whether you are working in proteomics, biopharmaceutical analysis, or peptide mapping, ZORBAX 300 ? columns offer the performance and flexibility needed to meet your most demanding separation challenges.