5300 Fragment Analyzer system for medium to high-throughput nucleic acid quality control
5300 Fragment Analyzer System
Using automated parallel capillary electrophoresis, the 5300 Fragment Analyzer system enables DNA quality control for a range of applications. These applications include NGS libraries, gDNA, cfDNA, and large DNA fragments. RNA quality can be checked by this system as well, where small RNA, total RNA, and mRNA vaccines are applicable for RNA integrity, sizing, and quantification analysis.
- Fragment Analyzer Systems
Product Details
- Medium- to high-throughput separation – Analyze 48 or 96 samples in parallel with a single, simple dilution step and easy instrument setup
- Unattended walk-away operation – Load up to three 96-sample microplates, no further user interaction is required
- Reduced sample analysis time – Apply batch processing features post electrophoresis to automatically generate results reports
- Easy adoption to changes in your workflow – Choose a shorter or longer array to maximize your runs regarding speed or resolution of individual samples
- Minimize hands-on time – Reduce the time needed for instrument setup with no daily array handling requirements and room-temperature-stable reagents
- Broad assay portfolio – Analyze samples ranging from gDNA, NGS libraries, and DNA fragments to total RNA, small RNA, and mRNA vaccines all on one platform
- High-resolution separation – Achieve separation resolution as good as 3 bp from fragments under 300 bp
- Objective quality assessment – Qualify your samples using quality metrics for RNA (RQN) and genomic DNA (GQN)
- Seamless switching between applications – Load two different gels into the instrument to use different kits within one system setup
- Comprehensive compliance services – Qualify instruments by IQ/OQ services for use in GMP environments
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- Key Literature
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Suitability Testing for IVT mRNA Analysis Using Agilent Fragment Analyzer Systems
This application note provides an example of a suitability study using the Agilent Fragment Analyzer system.
- Application Notes
- English
- 01 Aug 2025
- 750.77 KB
Quality Control in the PacBio HiFi Whole Genome Sequencing Library
Accurate and reliable next-generation sequencing (NGS) results rely on starting with high-quality samples.
- Application Notes
- English
- 02 Jul 2025
- 1.77 MB
CQA Assessment of LNP-Encapsulated IVT mRNA Using Agilent Fragment Analyzer Systems
This technical overview provides examples of CQAs for IVT mRNA, such as size, concentration, purity, and integrity, that can be addressed by the Agilent Fragment Analyzer system.
- Technical Overviews
- English
- 06 Mar 2025
- 381.88 KB
- Application Notes
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Goefei He
Ph.D., Principal Scientist, Pfizer Inc.
“The Fragment Analyzer rose really quickly as a frontrunner during our initial evaluations.”
View MoreDr. Kaat Leroy
Lab manager of the Functional Epigenetics Laboratory, KU Leuven
"Now, with the Fragment Analyzer, if you combine three plates, that’s almost 300 samples that you can process without even being next to the instrument.”
View MoreNicolas Smargiasso
QC Manager, Kaneka Eurogentec
“We can easily switch from one application to another [with the Fragment Analyzer system]”
View More