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This application note presents a streamlined LC/MS workflow for ASO purity assessment using the Agilent InfinityLab Pro iQ Plus LC/MS system and Oligo Analysis Accelerator (OAA) software for Agilent OpenLab CDS.
In this application note, HILIC is introduced as an orthogonal methodology and applied to the analysis of Exenatide, Semaglutide, and Tirzepatide.
This guide is valid for LC/SQ Mass Detector systems running OpenLab CDS 2.7 or 2.8 with LC/MS Driver 3.2
Release notes for the LC/SQ driver
LC/MS-based method for assessing the purity of an antisense oligonucleotide
Site preparation checklist for the InfinityLab Pro iQ Series LC/SQ mass detectors
This application note presents the analysis of peptide-related impurities for semaglutide with the Agilent 1290 Infinity II bio 2D-LC and InfinityLab LC/MSD XT.
In this application note, a method was presented to quantify major components as well as degradation products of lithium-ion battery electrolytes, with particular attention to achieving separation of all analytes within 14 minutes.
This Application Note describes a routine analysis workflow for pharmaceutical QA/QC labs.
In this application note, we employed an Agilent Infinity II 1260 Prime LC System coupled to an Agilent InfinityLab LC/MSD iQ for the analysis of CBD oil products manufactured for the pet industry. Here, we demonstrate excellent chromatographic...
| Chinese (Simplified) (China) | Complete (PDF) |
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Demonstrates simple and fast sample submission with the Agilent InfinityLab LC/MSD iQ for multiple users utilizing the sample purity workflow in an open-access environment.
| Chinese (Simplified) (China) | Complete (PDF) |
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Analysis of Additives in Polymer Using the Agilent 6120B Single Quadrupole MS and MassWorks.accurate mass elemental composition determination software
This application note evaluates the performance of an Agilent LC/MS in terms of achievable mass accuracy and spectral accuracy to enable unknown formula ID.
This guide provides an overview of the daily workflow using OpenLab CDS software
The novel approach presented in this method utilizes standard chromatographic methods and simple cost-effective single quadrupole mass spectrometer without sacrificing accuracy for the screening and quantitation of histamines in Gentamicin matrices.
Accurate Mass Full Spectral Monitoring and Analysis of Both the Analyte and Reference Standard with Ion Chromatography – Mass Spectrometry.
A robust microflow method for oligonucleotide analysis which dramatically reduces the consumption of HFIP and TEA. Carried out using the Axcend Focus LC ? coupled with the Agilent LC/MSD Pro iQ Plus.
A robust and cost-effective single quadrupole mass spectrometer reports on glycosylation relative abundances for monoclonal antibodies.
This study evaluates the stability of tirzepatide and semaglutide under various pH and storage conditions using the Agilent InfinityLab Pro iQ Plus LC/MS system.
This poster is a demonstration of Pro iQ Plus robustness & ruggedness against these factors over a series of 800 consecutive injections of analytes spiked in crashed plasma matrix.