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This application note demonstrates the signal recording of the xCELLigence RTCA eSight, enabling visualization and quantification of cell migration and invasion and the speed of wound closure healing.
This application note describes a novel real-time co-culture assay using RTCA eSight for interrogating NK92 immune cell invasion and cytotoxicity and migratory kinetic profiles based on ECM and effects of TME.
This study used the Agilent xCELLigence RTCA CardioECR system with human iPSC-derived cardiomyocytes (hiPSC-CMs) to evaluate cardiac safety/toxicity of antiviral drugs.
A demonstration of the use of the Agilent xCELLigence RTCA CardioECR system to compare functional profiles of contractility and electrophysiology between an PS-iPSC-CM disease model and its isogenic control.
A demonstration of how the Agilent xCELLigence RTCA eSight real-time imaging platform can be used to monitor induction of the unfolded protein response using a genetically encoded fluorescent sensor.
A demonstration of how the Agilent xCELLigence RTCA eSight real-time imaging platform can be used to monitor phagocytosis, using a model system comprising macrophages and E. coli cells conjugated to a pH-sensitive fluorescent dye.
A demonstration of how the eSight combines the strengths of real-time impedance monitoring with those of live cell imaging, to increase the information richness of your proliferation assays while simultaneously reducing the workload.
To determine if the stimulation of endogenously expressed GPCRs can be monitored by the xCELLigence system, cells were stimulated with various receptor agonists, triggering either Gs-, Gi-, or Gq-mediated downstream signals.
In this application note, we used the xCELLigence RTCA CardioECR system (CardioECR system) in conjunction with hiPS-CMs for the assessment of preclinical cardiac risks.
This application note presents a method for improving human-induced pluripotent
stem cell-derived cardiomyocyte (hiPSC-CM) maturation using the Agilent xCELLigence RTCA ePacer system.
Although cell therapies have shown great promise in clinical studies, challenges with the large scale manufacturing of these therapies still need to be addressed.
Dr. Daniel Hui from Tmunity Therapeutics addresses challenges with cell therapy development with an innovative CAR-T toolbox, using xCELLigence RTCA for measuring potency of immune cell therapies.