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This work describes and compares two methods, Fast LC and RapidFire, for the high-throughput sampling and desalting of oligonucleotides.
| Chinese (Simplified) (China) | Complete (PDF) |
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| Japanese (Japan) | Complete (PDF) |
| Korean (Korea) | Complete (PDF) |
This application note describes a high-throughput, ion-pairing-free method for oligonucleotide characterization using the Agilent RapidFire high-throughput MS system.
| Japanese (Japan) | Complete (PDF) |
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| Korean (Korea) | Complete (PDF) |
| Chinese (Simplified) (China) | Complete (PDF) |
Analysis of cytochrome P450 (CYP) inhibition is an important component of the drug discovery process as adverse drug-drug interactions can lead to termination of a drug development program, withdrawal from the market, or restrictions on therapeutic...
This guide provides safety information for the RapidFire 400 System.
This guide describes how to use the Agilent RapidFire Integrator software to analyze RapidFire data. This guide applies to RapidFire Integrator 4.3 or higher.
This guide includes procedures for setup, operation, and maintenance of the RapidFire 400 System.
RapidFire 400 Site Preparation Checklist
RapidFire 400 Chiller Site Preparation Checklist
Agilent's RapidFire High-throughput Mass Spectrometry system utilizes the Q-TOF MS to speed up metabolic stability data analysis by eliminating the need for MRM optimization.
A method for the ultrafast analysis of in vitro ADME samples using the Agilent RapidFire highthroughput MS system with the Agilent Ultivo triple quadrupole LC/MS for a reduced instrument footprint.
A modified RapidFire high throughput method that bypasses SPE desalting and enables a sub-2.5 second sample rate, making analysis of 35,000 samples a day possible
This work explores the simultaneous quantitation of a panel of nitrosamines in less than 15 seconds per injection.
During the drug discovery process, permeability assays such as Caco-2 (cell line) and PAMPA (parallel artificial membrane permeation assay) are utilized to mimic the absorption of potential drug candidates by the cells of the human intestine.
This application note describes analysis with the Agilent RapidFire high-throughput MS system using tubing with a smaller inner diameter (id).
Do you want to open new avenues for pursuing small molecule and protein drug targets—without using surrogates, radioactivity, coupled assays, or indirect measurements? The Agilent RapidFire 400 high-throughput mass spectrometry system delivers...
| Chinese (Simplified) (China) | Complete (PDF) |
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| Korean (Korea) | Complete (PDF) |
| Japanese (Japan) | Complete (PDF) |
A high-throughput, ion-pairing-free method for oligo characterization using Agilent RapidFire 400 and 6545XT QTOF system. The method uses MS-friendly, ammonium bicarbonate-based mobile phases and achieves a 12-second cycle time.
Development of a rapid screening method for select PFAS compounds in serum using the RapidFire 400 and the 6495D
Flyer that outlines the benefits of the Agilent Flexible Spend Plan.
Dr. Yoshiji Hantani of the Biological/Pharmacological Research Laboratories at the JT Central Pharmaceutical Research Institute tells how to use high-throughput screening (HTS) to discover new drug candidates.