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Describes a workflow for monitoring multiple mAb characteristics involving the Agilent 1290 Infinity II 2D-LC System.
- Publication Part Number: 5994-0947EN
- Created: 06 Feb 2020
- 1 MB
This application note describes a workflow for assessing critical quality attributes (CQAs) of intact adeno-associated viruses (AAVs), together with p...
- Publication Part Number: 5994-1980JAJP
- Created: 23 July 2020
- 1 MB
本文介紹了使用 Agilent 6530 Q-TOF 采集肽段數(shù)據(jù), 采用整合有 BioConfirm 的 MassHunter 定性軟件,通過軟件中的蛋白酶解產(chǎn)物比較功能,實現(xiàn)了對單克隆抗體藥物中二硫鍵連接的確證。此方法無需對樣品進行額外的標記,僅通過對還原和非還原組樣品的一級質譜進行比對,即可實...
- Publication Part Number: 5991-6068CHCN
- Created: 10 July 2015
- 628 KB