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This Technical Overview provides some tips and tricks on how to correctly apply the Agilent Buffer Advisor Software for the generation of pH gradients over a wide range
Method ransfer from a 1260 Infinity Bio-inert LC to a 1260 Infinity II Bio-inert LC showing proof of equivalency for charge variant analysis of rituximab
AdvanceBio Desalting - RP cartridges used for effective desalting of LC-separated monoclonal antibodies (mAbs) before characterization by mass spectrometry
Small –scale purification of a monoclonal antibody from a cell lysate and the subsequent analysis on a single instrument, the Agilent 1260 Infinity Bio-inert Quaternary LC.
This Application Note describes a high-resolution, pH-based separation of acidic and basic charge variants for monoclonal antibodies using the Agilent 1260 and BiomAb PEEK