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Accurately determine biomolecule aggregation and fragmentation with Agilent size exclusion columns.
A guide to find the right column for your characterization workflow. It includes advice and tips on method development, solvent choice, mobile phase modification, optimization, example separations, as well as ordering information.
Aggregate and Fragment Analysis of Adeno-Associated Viral Vectors using Size Exlusion is a critical analysis. Bio SEC-5 demonstrates reproducible separation and resolution of these AAV particles and aggregates.
Virus-like particles (VLPs) are highly structured protein particles that are self-assembled from one or more structural proteins, typically 20 to 150 nm in diameter.
This collection of 10 Agilent ‘a(chǎn)ggregate and fragment analysis’ app notes also includes our guide on how to perform SEC for biomolecule analysis.
Methods are given for the use of Agilent Bio-SEC columns, with LS, UV and RI detection, for quantification or quality control of protein aggregates
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