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Rapid mRNA capping analysis with a combined sample preparation and analysis time of only 75 minutes using an Agilent 6545XT AdvanceBio LC/Q-TOF.
This application note demonstrates the purification workflow of a single-stranded RNA ON by ion-pair reversed-phase HPLC.
Use of 6545XT LC/Q-TOF to analyze poly-A tail sequences formed by E. coli Poly-A Polymerase (PAP), which is a common component of in vitro transcription systems.
This application note shows that there are numerous variables available for optimization of the analytical conditions for oligonucleotides. The analyses were carried out on an Agilent 1290 Infinity II LC System with UV detection by DAD and an...
AdvanceBio Oligonucleotide with UV and MS eluents is ideal for oligonucleotides, with exceptional resolution, superior lifetime, compatible with 600 and 1200 bar.