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In this application note, we are investigating an antibody drug conjugate (ADC) with a cysteine linker. The Agilent 1290 Infinity II liquid chromatography system connected to a PLRP-S reversed phase liquid chromatography column was used to separate...
| Korean (Korea) | Complete (PDF) |
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| Chinese (Simplified) (China) | Complete (PDF) |
Analysis of an mAb (trastuzumab) and an ADC (trastuzumab emtansine) by size exclusion chromatography with online mass spectrometry (SEC-MS)
本文以半胱氨酸連接的抗體藥物偶聯(lián)物 (ADC) 為研究對象，使用天然質(zhì)譜法，通過 Agilent 6530 Q-TOF LC/MS 檢測 ADC 的完整分子量，并使用安捷倫 DAR 計算器軟件計算 ADC 的加權平均藥物/抗體比率(DAR)。