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1 - 13 of 13 results
The evaluation of different salt gradients was performed on the Agilent 1290 Infinity II Bio LC System and analyzed for resolution as well as reproducibility.
Method ransfer from a 1260 Infinity Bio-inert LC to a 1260 Infinity II Bio-inert LC showing proof of equivalency for charge variant analysis of rituximab
Online 2D-LC characterization of monoclonal antibodies using SEC in the first dimension and IEX in the second dimension
Small –scale purification of a monoclonal antibody from a cell lysate and the subsequent analysis on a single instrument, the Agilent 1260 Infinity Bio-inert Quaternary LC.
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The Agilent 1260 Infinity Bio-inert Quaternary LC with fluorescence detection and Agilent Bio SAX analyzed N-linked glycans with.excellent resolution and precision.
Comparative analysis using LC-QTOF/MS between innovator and biosimilar of Rituximab
Agilent Bio Mab WCX separates charged variants of an intact monoclonal antibody, followed by characterization with reversed-phase chromatography and UV/MS detection.
Agilent Bio Mab WCX separates charged variants of papain-digest monoclonal antibody, following by MS characterization of the charged variants with online desalting.
The charge heterogeneity provides a great challenge for the complete characterization of the monoclonal antibody (mAb).
Agilent Bio MAb columns, in an Agilent 1260 Infinity Bio-inert Quaternary LC, characterize the charge heterogeneity of IgG1monoclonal antibody...
| Publication Part Number | 5991-0895EN | |||
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This Application Note describes a high-resolution, pH-based separation of acidic and basic charge variants for monoclonal antibodies using the Agilent 1260 and BiomAb PEEK
| Publication Part Number | 5991-1407EN | ||
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Agilent applications chemists share their recommendations for an optimum LC system and its configuration for characterizing biomolecules. They also offer guidance on a generic method to get you started.
Explains IEX chromatography, column selection, mobile phase considerations, general rules of thumb for using IEX, and more.