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Online user guide for AdvanceBio SEC 1.9 μm columns.
An SEC method identifying innovator and biosimilar insulin analog was developed using an Agilent AdvanceBio SEC 130?, 7.8 × 300 mm, 2.7 μm column.
eBook containing workflows for released N-glycan analysis and sialic acid quantitation of biotherapeutics, native and denaturing mode SEC analysis of biotherapeutics, SEC analysis of small therapeutic proteins.
Comparison of HPLC method and a quick method developed using the Cary 60 UV-Vis
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| Korean (Korea) | Complete (PDF) |
| Chinese (Simplified) (China) | Complete (PDF) |
Describes a workflow for monitoring multiple mAb characteristics involving the Agilent 1290 Infinity II 2D-LC System.
Size Exclusion Chromatography Method Development of NIST mAb Using an Agilent AdvanceBio SEC 200 ?, 1.9 μm Column
Describes a comparison between the Agilent AdvanceBio SEC 200 ? 1.9 μm column and other vendors' SEC columns in terms of mAb and ADC analysis.
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| Chinese (Simplified) (China) | Complete (PDF) |
The improved separation of AdvanceBio standards and insulin using Agilent AdvanceBio SEC columns verses Agilent ZORBAX GF-250/450 columns.
Methods using Agilent AdvanceBio SEC columns are developed for the characterization of components of standard protein mixtures.
Size exclusion chromatography with light scattering detection was used to investigate the impact of varying SDS concentration on protein molecules.
An aggregate analysis workflow for SEC mobile phase optimization and characterization of mAb aggregation profiles
| Russian (Russia) | Complete (PDF) |
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| Japanese (Japan) | Complete (PDF) |
| Chinese (Simplified) (China) | Complete (PDF) |
| Chinese (Simplified) (China) | Complete (PDF) |
| Korean (Korea) | Complete (PDF) |
"This Application Note describes the quantification of aggregates in biotherapeutic
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| Chinese (Simplified) (China) | Complete (PDF) |
| Russian (Russia) | Complete (PDF) |
| Japanese (Japan) | Complete (PDF) |
Online 2D-LC characterization of monoclonal antibodies using SEC in the first dimension and IEX in the second dimension
A SEC method for determining the purity of PEG Granulocyte Colony Stimulating Factor using an Agilent AdvanceBio SEC column with aqueous mobile phase.
Agilent AdvanceBio SEC Protein Standards for AdvanceBio SEC Columns
"Agilent AdvanceBio SEC columns have been developed to provide optimum performance regardless of the instrument used.
Shorter 150 mm AdvanceBio SEC columns and higher flow rates of 1.5 mL/min increase sample throughput by 400%, from 1.3 days to under 8 hours.
| Chinese (Simplified) (China) | Complete (PDF) |
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| Russian (Russia) | Complete (PDF) |
| German (Germany) | Complete (PDF) |
| Portuguese (Brazil) | Complete (PDF) |
Agilent AdvanceBio SEC columns perform better in resolution, sensitivity, peak capacity and shape of mAbs and ADCs using low pressure LC and aqueous mobile phase.
Agilent AdvanceBio SEC Columns. End Uncertainty in Monoclonal Antibody Characterization.
| Russian (Russia) | Complete (PDF) |
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| Italian (Italy) | Complete (PDF) |
| French (France) | Complete (PDF) |
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| Chinese (Simplified) (China) | Complete (PDF) |
Analysis of an mAb (trastuzumab) and an ADC (trastuzumab emtansine) by size exclusion chromatography with online mass spectrometry (SEC-MS)
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