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The development and manufacturing of biosimilars require comparability studies with innovator biotherapeutic products.
- Publication Part Number: 5994-1495EN
- Created: 15 Oct 2024
- 2 MB
| Korean (Korea) | Complete (PDF) |
|---|---|
| Chinese (Simplified) (China) | Complete (PDF) |
A Comparative Study of the Intact Mass, Subunit Mass, and Released Glycans of Two Rituximab Biosimilars Using High-Resolution LC/MS
- Publication Part Number: 5994-1653EN
- Created: 15 Oct 2024
- 1 MB
| Chinese (Simplified) (China) | Complete (PDF) |
|---|---|
| Korean (Korea) | Complete (PDF) |
This application note describes a novel 2D-LC approach using MHC and subsequent SEC desalting for native MS analysis.
- Publication Part Number: 5994-4328EN
- Created: 30 Nov 2021
- 2 MB
This application note presents different approaches to native mass spectrometry.
- Publication Part Number: 5994-3036EN
- Created: 25 Mar 2021
- 2 MB
This application note describes a robust LC/MS method for the analysis of native mAb-siRNA conjugates.
- Publication Part Number: 5994-2155EN
- Created: 24 June 2020
- 3 MB
This application note describes a robust LC/MS method for the analysis of native protein analysis.
- Publication Part Number: 5994-1739EN
- Created: 12 Mar 2020
- 948 KB
Describes a workflow for monitoring multiple mAb characteristics involving the Agilent 1290 Infinity II 2D-LC System.
- Publication Part Number: 5994-0947EN
- Created: 06 Feb 2020
- 1 MB
This application note presents the use of the Agilent 6560 ion mobility LC/Q-TOF to analyze the formation of multimers of bovine serum albumin (BSA) in various mobile phases.
- Publication Part Number: 5994-1554EN
- Created: 02 Jan 2020
- 4 MB
An automated workflow for the analysis of protein phosphorylation from sample preparation with phosphopeptide enrichment to analysis by IMS.
- Publication Part Number: 5994-1617EN
- Created: 26 Nov 2019
- 2 MB
The development and manufacturing of biosimilars require comparability studies with innovator biotherapeutic products.
- Publication Part Number: 5994-1496EN
- Created: 25 Oct 2019
- 2 MB
| Korean (Korea) | Complete (PDF) |
|---|---|
| Chinese (Simplified) (China) | Complete (PDF) |
This application note describes a method for quantitative analysis of intact monoclonal antibodies (mAbs) in a serum matrix.
- Publication Part Number: 5994-1249EN
- Created: 27 Sep 2019
- 1 MB
Presents the use of the Agilent 7100 CE Instrument with MS detection for direct MS determination of monoclonal antibody charge variants.
- Publication Part Number: 5994-0672EN
- Created: 01 Feb 2019
- 2 MB
| Chinese (Simplified) (China) | Complete (PDF) |
|---|---|
| Japanese (Japan) | Complete (PDF) |
This app note presents a complete high-throughput workflow solution to analyze a variety of mAb products.
- Publication Part Number: 5991-7813EN
- Created: 19 Nov 2018
- 1 MB
This study demonstrates an HCP analysis workflow
- Publication Part Number: 5991-9300EN
- Created: 02 July 2018
- 2 MB
| Japanese (Japan) | Complete (PDF) |
|---|---|
| Chinese (Simplified) (China) | Complete (PDF) |
This application note demonstrates three approaches to quantitatively understand the glycosylation present for a given mAb.
- Publication Part Number: 5991-8796EN
- Created: 22 Jan 2018
- 1 MB
This app note presents a high-throughput workflow that enables simultaneous, highly reproducible sample digestion and cleanup.
- Publication Part Number: 5991-7811EN
- Created: 15 Feb 2017
- 2 MB
| Korean (Korea) | Complete (PDF) |
|---|
In this application note, we are investigating an antibody drug conjugate (ADC) with a cysteine linker. The Agilent 1290 Infinity II liquid chromatography system connected to a PLRP-S reversed phase liquid chromatography column was used to separate...
- Publication Part Number: 5991-6559EN
- Created: 16 Sep 2016
- 710 KB
| Korean (Korea) | Complete (PDF) |
|---|
Using Automated Affinity Purification, LC/MS analysis, and Novel DAR Calculation Software
- Publication Part Number: 5991-6621EN
- Created: 29 Apr 2016
- 7 MB
| Korean (Korea) | Complete (PDF) |
|---|
Comparative analysis using LC-QTOF/MS between innovator and biosimilar of Rituximab
- Publication Part Number: 5991-6522EN
- Created: 01 Jan 2016
- 1 MB
Describes the identification and quantitation of chemically-modified recombinant mABs with the Agilent 6545XT AdvanceBio LC/Q-TOF and Agilent MassHunt...
- Publication Part Number: 5994-0406JAJP
- Created: 13 Mar 2019
- 1 MB