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The Agilent AdvanceBio SEC column together with the Agilent 1260 Infinity II Bio-inert System is an ideal combination for the aggregate analysis of ADCs
Presents a method for the rapid analysis of a monoclonal antibody using the Agilent AdvanceBio SEC 200 ? 19 μm column.
Comparison of HPLC method and a quick method developed using the Cary 60 UV-Vis
This application note describes a robust LC/MS method for the analysis of native protein analysis.
Agilent-NIST mAb application compendium
Size Exclusion Chromatography Method Development of NIST mAb Using an Agilent AdvanceBio SEC 200 ?, 1.9 μm Column
Describes a comparison between the Agilent AdvanceBio SEC 200 ? 1.9 μm column and other vendors' SEC columns in terms of mAb and ADC analysis.
Size exclusion chromatography with light scattering detection was used to investigate the impact of varying SDS concentration on protein molecules.
An aggregate analysis workflow for SEC mobile phase optimization and characterization of mAb aggregation profiles
"This Application Note describes the quantification of aggregates in biotherapeutic
Agilent AdvanceBioSEC columns used for fast, high resolution, sensitive, and reproducible separation and quantitation of mAbs and Antibody Drug Conjugate,
A SEC method for determining the purity of PEG Granulocyte Colony Stimulating Factor using an Agilent AdvanceBio SEC column with aqueous mobile phase.
Shorter 150 mm AdvanceBio SEC columns and higher flow rates of 1.5 mL/min increase sample throughput by 400%, from 1.3 days to under 8 hours.
Agilent AdvanceBio SEC Columns. End Uncertainty in Monoclonal Antibody Characterization.
High resolution and sensitive size exclusion chromatography separates and quantitates rituximab aggregates/degradants in a bioinert LC with an AdvanceBio SEC column.
Methods are given for the use of Agilent Bio-SEC columns, with LS, UV and RI detection, for quantification or quality control of protein aggregates
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