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Research highlight confirming the critical role of metabolic fitness in CAR-NK cells and its importance to achieve superior clinical outcomes in immunotherapy.
This application note introduces a workflow that uses the XF Real-Time ATP rate assay data for identifying metabolic modulator and drug targets.
Learn about a customized workflow to standardize the identification/investigation of mitochondrial toxicity using Agilent Seahorse XF technology.
| Chinese (Simplified) (China) | Complete (PDF) |
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CAR T-cell manufacturing conditions are critical to differentiation, metabolic fitness, and cytotoxic function, enhancing therapy efficacy and production efficiency.
Poster for the annual meeting (2025) of American Association of Immunologists, showing exhausted T cells generated through chronic beads activation have a distinct and consistent metabolic phenotype that can be assess using XF Pro and T Cell...
AACR 2025 poster: Chronic anti-CD3/CD28 stimulation during cell expansion generates exhausted T cells with a distinct metabolic and cytotoxic phenotype
The poster introduces a multiparametric workflow that allows for evaluating contractility, viability, and metabolic function using validated human iPSC-derived cardiomyocytes to better understand the mechanisms associated with drug-induced...
we demonstrated consistent production of CAR T-cells using the functionally closed and automated cell manufacturing Lonza Cocoon platform, using a novelcombination of cell analysis parameters obtained from an Agilent xCELLigence RTCA system, a...
This editorial showcases Agilent solutions for metabolic modulation enhancing CAR T-cell activation, persistence, and serial killing for improved cancer immunotherapy
CAR-TCR 2024 Poster. We demonstrated the successful production of CAR T-cells using the Lonza Cocoon system. Additionally, CAR T-cell in-process analyses and critical process parameters were evaluated using the combination of a flow cytometer, a...
The Agilent Seahorse XF Pro instrument performance specification sheet.
Learn about the principle and parameter calculations in the Agilent Seahorse XF Mito Tox assay solution used to assess mitochondrial toxicity
| Chinese (Simplified) (China) | Complete (PDF) |
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Case study about CAR-T therapy
關(guān)于 CAR-T 療法的案例研究