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This Application Note describes a simple method for the analysis of disulfide linkages in monoclonal antibodies (mAbs) by reversed phase HPLC.
- Publication Part Number: 5991-1694EN
- Created: 15 Oct 2024
- 961 KB
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This work describes a high flow LCMS method to demonstrate the high resolution mass analysis of mAbs with good chromatography and its utility in analysis of Biosimilar mAbs.
- Publication Part Number: 5991-4266EN
- Created: 01 July 2014
- 310 KB
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A comparison of the separation and sequence coverage of glycoproteins by reversed-phase and HILIC demonstrates the utility of HILIC.
- Publication Part Number: 5991-2085EN
- Created: 10 May 2013
- 407 KB
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Fast and efficient LC TOF/MS characterizes intact and digested IgG to identify glycoform masses and profiles. mAb-glyco chip analysis built a glycan accurate mass database.
- Publication Part Number: 5991-2323EN
- Created: 23 Apr 2013
- 475 KB
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Accurate mass intact protein analysis using 6550 iFunnel Q-TOF
- Publication Part Number: 5991-2116EN
- Created: 29 Mar 2013
- 613 KB
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Rapid reversed-phase separations of intact and reduced monoclonal antibodies (mAbs) were optimized using Agilent ZORBAX RRHD 300SB-C3 columns.
- Publication Part Number: 5990-9667EN
- Created: 13 Feb 2012
- 364 KB
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JM
- Publication Part Number: 5990-9668EN
- Created: 07 Feb 2012
- 807 KB
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Evaluation of the thermal stability and lifetime of the columns subjected to 100 cycles of 25-minute long gradient cycles at either 80 °C (PLRP-S) or 60 °C (all other columns)
- Publication Part Number: 5990-7764EN
- Created: 19 May 2011
- 1 MB
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