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This application note describes a high-throughput, ion-pairing-free method for oligonucleotide characterization using the Agilent RapidFire high-throughput MS system.
Analysis of cytochrome P450 (CYP) inhibition is an important component of the drug discovery process as adverse drug-drug interactions can lead to termination of a drug development program, withdrawal from the market, or restrictions on therapeutic...
This guide describes how to use the Agilent RapidFire Integrator software to analyze RapidFire data. This guide applies to RapidFire Integrator 4.3 or higher.
Agilent's RapidFire High-throughput Mass Spectrometry system utilizes the Q-TOF MS to speed up metabolic stability data analysis by eliminating the need for MRM optimization.
A method for the ultrafast analysis of in vitro ADME samples using the Agilent RapidFire highthroughput MS system with the Agilent Ultivo triple quadrupole LC/MS for a reduced instrument footprint.
A modified RapidFire high throughput method that bypasses SPE desalting and enables a sub-2.5 second sample rate, making analysis of 35,000 samples a day possible
During the drug discovery process, permeability assays such as Caco-2 (cell line) and PAMPA (parallel artificial membrane permeation assay) are utilized to mimic the absorption of potential drug candidates by the cells of the human intestine.
Do you want to open new avenues for pursuing small molecule and protein drug targets—without using surrogates, radioactivity, coupled assays, or indirect measurements? The Agilent RapidFire 400 high-throughput mass spectrometry system delivers...