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Description of an ultrafast method for performing enzyme inhibition selectivity screening using the RapidFire SPE/MS/MS system.
In 2021 Agilent announced HRdm 2.0 enabling researchers to obtain drift resolutions as high as 250 on an LC time scale, while continuing to obtain accurate, precise, and reproducible CCS values. HRdm 2.0, combines demultiplexing and deconvolution...
This application note describes the assignment of exact structures of N-glycan released from glycoproteins of complex biological sample using ion mobility-mass spectrometry (IM-MS) exploiting unique arrival time distributions (ATDs) for each glycan.
Glycopeptide Characterization of mAb by LC/Q-TOF
The performance of the Agilent 6495B Triple Quadrupole for peptides with high m/z product ions, showing the benefits of having amass range up to m/z 3,000.
| Korean (Korea) | Complete (PDF) |
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A comprehensive untargeted approach using high-resolution LC/MS and GC/MS was applied to study differences in food compositions from distinct diets.
| Korean (Korea) | Complete (PDF) |
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Clone selection is important during Monoclonal antibodies development. Proof of principle using 2D-LC/MS solution is demonstrated for identifying the correct clone.
| Korean (Korea) | Complete (PDF) |
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Extractables analysis using high resolution LC/MS system and sample comparison using Agilent Mass Profiler Software.
Application note for the LC/MS Walk-Up Solution from Agilent - MassHunter software
本文介紹了采用配置 APCI 源的 Agilent 6470 三重四極桿液質(zhì)聯(lián)用系統(tǒng)，同時檢測沙坦藥物中六種亞硝胺類基因毒性雜質(zhì) NDMA、NDEA、NMBA、NEIPA、NDIPA 和 NDBA 的方法。
本文介紹了采用 Agilent Ultivo 三重四極桿液質(zhì)聯(lián)用系統(tǒng)檢測氯沙坦鉀中的亞硝胺類雜質(zhì) NMBA 的方法。該方法采用常規(guī) ESI 源，即可獲得滿足檢測要求的分析結(jié)果，且方法簡單、特異性高、靈敏度高，大大優(yōu)于 FDA 官網(wǎng)公布的限量要求。
本文詳細(xì)的介紹了蛋白（肽段）定量的意義及出現(xiàn) MRM 質(zhì)譜技術(shù)平臺的緣由、MRM 肽段定量的基本原理、安捷倫 MRM 肽段定量的完整定義以及安捷倫 LC/QQQ 肽段定量應(yīng)用實(shí)例等。