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Presents the use of the AdvanceBio HIC column to resolve monoclonal antibody variants from their native form without mAb digestion into subunits.
This application note demonstrates three approaches to quantitatively understand the glycosylation present for a given mAb.
The charge heterogeneity provides a great challenge for the complete characterization of the monoclonal antibody (mAb).
The Agilent AdvanceBio Peptide Mapping column separates mAb tryptic digests at low system pressures, providing UHPLC performance from HPLC operating conditions.
| Publication Part Number | 5991-3585EN | |||
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Peptide mapping is the common analytical technique for characterizing biologic therapeutic proteins.
| Publication Part Number | 5991-3600EN | ||||
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Accurate mass intact protein analysis using 6550 iFunnel Q-TOF
| Publication Part Number | 5991-2116EN | |||
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