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This application note presents different approaches to native mass spectrometry.
This application note describes a method for automated MHC-I associated peptide enrichment using the Agilent AssayMAP Bravo platform with large-capacity (25 μL) cartridges for immunopeptidomics analysis.
This application note describes a robust LC/MS method for the analysis of native mAb-siRNA conjugates.
This application note describes a robust LC/MS method for the analysis of native protein analysis.
Describes a workflow for monitoring multiple mAb characteristics involving the Agilent 1290 Infinity II 2D-LC System.
This application note presents the use of the Agilent 6560 ion mobility LC/Q-TOF to analyze the formation of multimers of bovine serum albumin (BSA) in various mobile phases.
An automated workflow for the analysis of protein phosphorylation from sample preparation with phosphopeptide enrichment to analysis by IMS.
The development and manufacturing of biosimilars require comparability studies with innovator biotherapeutic products.
| Korean (Korea) | Complete (PDF) |
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| Chinese (Simplified) (China) | Complete (PDF) |
This application note describes a method for quantitative analysis of intact monoclonal antibodies (mAbs) in a serum matrix.
This app note presents a complete high-throughput workflow solution to analyze a variety of mAb products.
| Chinese (Simplified) (China) | Complete (PDF) |
|---|---|
| Japanese (Japan) | Complete (PDF) |
Presents the use of AdvanceBio Desalting-RP cartridges to pretreat mAb and ADC samples before MS analysis.
Presents the use of the Agilent Bio SEC-3 column to aid HRMS characterization of mAbs and ADCs.
An Agilent LC system, ZORBAX column and optimized LC gradient were used for fast separation of blood plasma lipids with 15 minutes cycle time injection-to injection.
This study demonstrates an HCP analysis workflow
| Japanese (Japan) | Complete (PDF) |
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| Chinese (Simplified) (China) | Complete (PDF) |
This application note demonstrates three approaches to quantitatively understand the glycosylation present for a given mAb.
| Chinese (Simplified) (China) | Complete (PDF) |
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This app note presents a high-throughput workflow that enables simultaneous, highly reproducible sample digestion and cleanup.
| Korean (Korea) | Complete (PDF) |
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| Japanese (Japan) | Complete (PDF) |
| Chinese (Simplified) (China) | Complete (PDF) |
In this application note, we are investigating an antibody drug conjugate (ADC) with a cysteine linker. The Agilent 1290 Infinity II liquid chromatography system connected to a PLRP-S reversed phase liquid chromatography column was used to separate...
| Korean (Korea) | Complete (PDF) |
|---|---|
| Chinese (Simplified) (China) | Complete (PDF) |
Using Automated Affinity Purification, LC/MS analysis, and Novel DAR Calculation Software
| Korean (Korea) | Complete (PDF) |
|---|
Comparative analysis using LC-QTOF/MS between innovator and biosimilar of Rituximab
Analysis of an mAb (trastuzumab) and an ADC (trastuzumab emtansine) by size exclusion chromatography with online mass spectrometry (SEC-MS)